As researchers learn more and more about the structure, chemical composition and features of stem cells, more and more is revealed to them in terms of their control. Today, a team of microbiology scientists from the University of Edinburgh conducted a rather interesting experiment to disable one important mechanism in stem cells – namely, to deactivate a regulatory molecule that controls the immune impulse of cell protection when it is in danger. The results of the study, being very positive, promise in a short time to become the basis on which even more efficient and interesting experiments will be conducted.
It is worth noting that, unlike any other cells in the body, stem cells do not have their own defense system and cannot activate the immune impulse for this defense – on the other hand, when some viruses interact, they still send this impulse, which complicates the work with stem cells, because in this way it becomes difficult to modify them in the laboratory.
That is why Scottish experts conducted research according to which they found a special protein called MAVS, which in turn triggers the activation impulse of the regulatory miR-673 molecule. And this molecule, in turn, activates the immune defense of the stem cell, not allowing it to manipulate as needed by scientists. After several sessions of experiments-observations on embryonic-type stem cells belonging to mice, the scientists discovered that removing this regulatory molecule leads to a significant ease of working with the cell itself.
In other words, by deactivating this molecule, specialists can more easily manipulate cells, thus changing their structure and chemical composition much faster and easier. And this, in turn, leads to significantly more effective results in the transformation of a stem cell into something else. However, it remains to wait for new results.