News & Events
Scientists have identified the thinness gene and are actively exploring it
- June 9, 2020
- Posted by: Wiley M. Wagner
- Category: Science
Among the world's population, there are about 1% of people who, despite the lack of systematic physical training and the presence of a large amount of consumed fat and carbohydrates, still manage to remain thin, and at the same time physically healthy. Being objects is dependent on many people, they also represent a certain scientific interest on the part of many teams of biologists. That is why today a joint team of biologists from various European universities presented a study according to which the answer to such a rapid metabolism lies in the low production of one specific gene called ALK.
This gene is actually a whole family branch of genes of various directions, which is mostly associated with metabolism and metabolic processes in the body. The research team, having selected more than 50 thousand cases from the Estonian biobank with the consent of the owners of these cases, and also conducted a comparative study on mice, was able to establish that this particular gene is responsible for maintaining thinness and health even with a large amount of absorbed food and in the absence of training.
They found that the main center of gene expression is the so-called paraventricular nucleus located in one of the sections of the hypothalamus in the brain. In order to establish how strongly blocking or reducing the functioning of a given gene can affect body weight and other metabolic aspects, the scientists conducted several lengthy sessions on experimental mice, establishing that the almost complete cessation of the production of this gene in fact allows preserving the original thinness of the body, while maintaining all normal metabolic indicators.
Scientists suggest that a similar result can be achieved in the context of human anatomy, since this is indirectly indicated by the data of patients from the same Estonian state biobank – on the other hand, the study still has many questions regarding the possibility of modifying this gene from the outside using the same technique inducing altered hormones. So it remains only to wait for the end of the current branch of this study.