Microbiologists from the University of Washington today presented a really interesting study devoted to considering the possibility of increasing life expectancy and increasing the activity level of old rats – at the expense of young individuals, of course. The basis of the new study is the use of young blood of young individuals, but instead of directly dealing with blood transfusion – in the best traditions of ancient and medieval myths – scientists came to the conclusion that it is enough to increase the production of a certain enzyme that is present in the blood of young rats to a fairly high degree.
Their preliminary studies have shown that this enzyme decreases in production over time – and at the same time, the level of activity of rats decreases. Vision, hearing, motor skills and metabolism – all these and some other aspects of the life of old individuals are becoming increasingly inhibited and difficult for themselves. But young rats have no problems with this, because the so-called eNAMPT enzyme is synthesized in their blood to a rather high degree, which plays a significant role in the implementation of cellular activity and energy metabolism, as shown by preliminary results of research by specialists.
Thus, having conducted short and not very effective blood transfusion sessions for old individuals from young individuals, specialists from Washington University concluded that it is best to engage in the artificial production of the eNAMPT enzyme in the blood of old individuals – which they managed to create in the laboratory, without some difficulties and compromises.
It is worth noting that despite the somewhat controversial nature of the changes, the research mission itself was successful, since scientists actually managed to develop this enzyme – albeit with some limitations. Such successful experimental results allow us to hope that very soon similar studies will be carried out preliminary in humans, since we have a biology similar to mice.