Genetic specialists at Stanford University have found a new way to modify pairs of genes and genetic compounds that form various cancers in the lungs of mice, which served as the first experimental subjects – and then they were able to track individual cells in the resulting cancerous tumor. This successful result is really promising for a deeper understanding of the development of cancer cells as such and for the development of potentially more effective anti-cancer types of drugs and therapies – in particular, this will significantly expand the study of genetic diversity in the formation of cancer.
An article with this new methodology for detecting and modifying genes related to the formation of cancer has already been published in the journal Nature Genetics, where the project manager, Monte Winslow, noted that the team managed to combine the well-known in the scientific community technology for modifying and modifying genes called CRISPR- Cas9 with the traditional DNA decoding technique, which was proposed to the team in a slightly modified and improved form by the Department of Biology of the same Stanford University.
The ability to operate on the functionality of CRISPR technology in relation to genes and gene links, coupled with the rapid decoding of individual genes using DNA decoding, allowed scientists to quickly find the appropriate genes and gene links that can be most directly associated with the emergence and development of cancer cells. At least preliminary mouse tests have confirmed this potential.
It is worth noting the fact that at the moment, scientists are more focused on further improving this technology, adding to it a greater degree of flexibility in finding and alternating genes and gene compounds. In addition, scientists are faced with an additional complexity, which is to somewhat facilitate and reduce the cost of the process of working with genes within the framework of this technology – the fulfillment of this goal would significantly advance CRISPR as such.