One of the most interesting and unusual mysteries in modern medicine is the mystery of why women on average are more likely to suffer from various autoimmune diseases compared to men – because their chances of acquiring such a disease are about nine times higher than in men. And today, a team of microbiological researchers from the University of Michigan in the USA presented the results of their recent experiment on mice, which was based on an attempt to find certain regulatory genes or immune cells that trigger the autoimmune process in the body – and what is characteristic, they are really found
The fact is that during their observations of transgenic mice that induced symptoms similar to systematic lupus – one of these autoimmune diseases – the experts determined that it was a large number of the VGLL3 switch hormone that triggers this process. Moreover, most of this molecular switch is found precisely in the cells of the skin, but despite its remote locality, it can still spread to the tissues of the internal organs – which implies various problems with their consistent failure in autoimmune diseases.
The ability to interact in a certain way with this VGLL3 switch, and even change it in some way, at the moment seems to be the top priority for researchers on this issue. In addition, they are ready to begin more detailed studies on autoimmune diseases, which have a large area of development.
It is worth noting that, despite all the results, the team of researchers also does not overlook the possibility that the above-mentioned molecular switch VGLL3 works in tandem with other or other molecular compounds — to answer this part of the question, you must first carry out the appropriate research than specialists and will be engaged.