News & Events
Presents a medicine that passively supports muscle tone
- August 22, 2019
- Posted by: Wiley M. Wagner
- Category: Science
A rather sad fact is that as a person approaches old age, his total muscle mass begins to decrease steadily, and his muscles become less strong and elastic – and this begins to happen after 35-40 years. However, experts from the medical college at the University of Texas have their own answer to the question of how to effectively prevent this degenerative pace. The fact is that they managed to identify a special protein called nicotinamide N-methyltransferases, which is the protein responsible for the development of the entire process of muscle tissue degeneration over time.
Studying the properties and work of this protein, experts found that it can be controlled with some degree of success by acting on it with a special inhibitor under the designation NNMTi-inhibitor – which was also previously developed by specialists as a test protein inhibitor aimed at changing the intracellular function of various protein families. By acting with this inhibitor on the protein presented in experimental rats of advanced age, they noticed that after a few days the muscle fibers of rats became both more flexible and strong, even in comparison with the second control group of younger rats given a placebo.
They noticed that their muscle tissue became stronger by an average of 70%, and this despite the fact that the inhibitor acted on muscle tissue a little differently, working with different sides of the protein compound. However, scientists still have to slightly refine their original formula of the medicine, then in theory they switched to trials in humans, when it has finally proved itself.
The research article was already published in the latest issue of the journal Biochemical Pharmacology, where specialists explained in detail all the features and aspects of the work of their new protein inhibitor – which, by the way, already has every chance of becoming a really useful and multifunctional compound for use in various areas of activity and in various areas of modern applied medicine.