News & Events
Intestinal bacteria control depression
- May 11, 2019
- Posted by: Wiley M. Wagner
- Category: Science
For many years, scientists in the field of behaviorism and neurobiology have in one way or another raised the question of the potential relationship between a certain condition and the profile of intestinal bacteria, and depression. Today, a team of specialists from the Children's Hospital of Philadelphia in the United States presented the results of their research on some specific markers of such a relationship – scientists actually discovered them and illustrated how different combinations and profiles of intestinal bacteria can affect stress tolerance and susceptibility to depressive states with an example experimental rodents.
It is worth noting that the study initially focused mainly on the standard relationship between inflammation of certain brain areas and susceptibility to depression, but soon switched to searching for specific intestinal bacteria and their combinations, which are more typical of rodents suffering from depression. And they have found such! For example, scientists have noticed that most rodents suffering from depressive disorder – including induced – have a significantly higher concentration of bacteria of the Clostridia family, along with many others.
Having transplanted this “depressive” profile of bacteria to those rodents that have never suffered from it, the scientists subsequently noticed that they began to develop alternative behavior and clearly visible depressive patterns of behavior in certain situations. Thus, having made their own experiment-study, the experts once again proved that the relationship between intestinal bacteria and depression exists.
However, they also face certain problems in their research – for example, the need to compile the most accurate statistical map of the study, in which they could more accurately and easily find the most problematic families and combinations of intestinal bacteria. Of course, in relation to a person, the results will be approximately the same, although it is still far from clinical tests.