Osteoarthritis is one of the most serious and common diseases among older people who begin to experience problems with the flexibility and stamina of their joints and cartilage. In particular, the disease is characterized by a marked decrease in this flexibility and durability of the cartilage tissue, often paralyzing certain areas. That is why a talented team of researchers from the Salk Institute in the USA presented the results of their new experimental anti-arthritis therapy, aimed not only at combating osteoarthritis, but also with a whole range of similar diseases – and based on the emphasis on the use of special molecules.
In particular, we are talking about the combined use of two drug molecules called alpha-KLOTHO and TGF beta receptor 2 – early studies using each of these molecules gave positive results when they were used separately, and therefore the researchers decided to combine their properties into one formula and thus create a more complex version of the molecule.
According to preliminary tests in mice, experts found that the presented combined formula of molecules actually allows not only to significantly increase the degree of flexibility of cartilage that underwent deformation, but also to increase the number of structural cells that do not allow further cartilage tissue to wear out so quickly. At the same time, it is worth noting that the results obtained were achieved without the use of third-party expensive drugs or laboratory-medical type materials.
It is assumed that approximately the same level of efficiency can be achieved in humans, since mouse and human biologies are largely similar. However, at this point in time, specialists will have to further improve the formula of their combined molecule, since at the current stage there are still some inaccuracies and unpredictable triggers. Be that as it may, there is little doubt that specialists will soon present the final version of their anti-arthritis medicine.