Given the fact that asthma is a common and frequently encountered disease, it becomes even incredible that we know so little about the mechanism of its formation. In order to clarify some points related to this, a team of medical specialists from the Human Cell Atlas initiative decided to create a new detailed map of the lungs affected by asthma. Moreover, the specialists conducted a truly comprehensive analysis and made up several individual cell maps illustrating the difference between healthy cells and infected cells – and on the basis of this, they were then able to create a universal map tool for studying the internal cellular processes in asthma.
Thus, the experts analyzed more than 36 thousand individual cells from the nasal zone and the three zones of the lungs in those people who did not suffer from asthma – in order to make a reference base of reference. Then they repeated the collection of tests from patients suffering from asthma and other respiratory illnesses in one form or another. Then the scientists compared two databases and found that there is a new cellular condition that can exacerbate the symptoms of the disease.
Scientists have discovered that inflammatory immune cells called Th2 in asthmatics are produced much faster and more active, while affecting more tissues in the respiratory tract – and this means that they themselves were simultaneously infected, thus unable to stop the original source of infection. It is this state and process that is studied by experts who are striving to provide something really interesting and unusual in terms of end results – it is quite possible that the process presented is the key to the development of asthma.
On the other hand, the preparation of such a detailed map of the lungs is quite a difficult task, since it involves a constant comparison and study of some other statistical and reference databases. So far, it remains to wait for the final completion of the work of medical specialists and, on the basis of their findings, to build their own on this case.