Changes in liver metabolism can prevent diabetes

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Many modern people know firsthand at least in general terms how to eat and stay healthy – however, those who love foods rich in fats and sugar are often interested in various compromises. So the microbiologists from the Max Planck Institute, specializing in studying the features and patterns of metabolism of internal organs, decided to make an interesting experiment in mice, aimed at determining whether it is possible to consume such dangerous foods and still remain healthy. The test results surprised a lot of the experts themselves.

The fact is that the consumption of large amounts of fats and sugar leads to the expansion of adipose tissue and the fats themselves in the body, which cover the internal organs and significantly reduce the level of reaction to insulin – and this can cause type 2 diabetes and other diseases of a similar spectrum. And these diseases are formed by the action of the so-called ceramides – special fats that regulate this process. Researchers, using the example of rodents, tried to find out whether it is possible to block the process of their synthesis in the body in order to continue to consume a diet saturated with fats and to remain healthy.

After several test sessions, they found that disabling one of the synthesizing processes in the liver – the so-called 6 type of synthesis of ceramides – can in fact lead to significantly faster absorption of fats and sugar. Rodents who underwent these modifications showed a higher level of physical activity and overall health despite consuming a lot of fat.

Thus, the specialists actually managed to significantly change the fat metabolism of the liver, while achieving more than solid and stable results in terms of fat absorption and ceramides. It is not yet clear what the results will be in relation to people, but the current study and its results clearly demonstrate that, perhaps, in the future, a change in metabolism may become one of the most common medical practices.

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