News & Events
An unusual experiment with a fecal graft.
- May 17, 2019
- Posted by: Wiley M. Wagner
- Category: Science
A rather interesting and unusual study was conducted by obesity specialists from several US universities – the fact is that they made up an experiment in which 22 people who were obese but did not differ from each other took part. The experiment was to check whether the changes in the characteristics and composition of the intestinal bacteria environment actually can help to effectively reduce the weight of participants – as was done in the format of integrating the fecal samples of other thin people into the intestinal environment of participants suffering from obesity. And the results were quite interesting.
Although they can not be called particularly encouraging, because even after the expiration of a twelve-week period, none of the 22 participants in the experiment could lose weight by taking a fecal graft, previously owned by thin and healthy people. Moreover, during the entire experiment, only half of the participants received this fecal transplant, while the other half received only placebo capsules with zero effect.
In particular, researchers were interested, they can only change the features and nuances of the work of glucagon peptide 1 called GLP1 – because it is this peptide that is responsible for the brain expressing feelings of satisfaction after eating, a disruption in the work of which with a high degree of probability causes disturbances in the regulation of nutrition, which may cause additional obesity when overeating. But despite the fecal sample transplantation of thin people to the participants of the experiment, none of them showed confident indicators of weight loss.
However, this does not mean at all that the experiment did not give at least some positive results, because after the observation period expired, the doctrine noticed that the absolute majority of the experiment participants had significantly improved metabolism, due to the fact that the fecal transplant underwent some healthy colonies of intestinal bacteria, which changed the intestinal environment of the participants for the better.