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The use of various anticancer drugs and compounds in the protective shell of certain peptides is one of the most visible and important priorities of the vast majority of specialists and teams of specialists in the field of modern oncology. However, not all such drugs and compounds literally survive to provide their properties to infected cells – thereby dying in a highly acidic environment. However, oncologists from the Higher Technical School of Zurich today presented their new study on the development of a new type of such anti-cancer peptide drug.
We are talking about the use of nano particles of platinum, which, being prone to oxidation, becomes a really big threat to cancer-infected cells. However, there is one important and significant drawback – these nanoparticles also endanger healthy cells, thereby harming the general condition of the body. In order to overcome this barrier, experts from Zurich proposed the use of a special peptide – not yet officially named in order to preserve scientific secrets – which would serve as both a protective shell and a preservative compound to restrain the properties of oxidized platinum.
The idea was quite simple – to launch non-oxidized platinum nanoparticles into the area affected by the cancer, and then exposing these nanoparticles to the highly active and acidic environment of the cancer cells, make them oxidize, thereby starting to work exclusively when they enter the cells affected by the cancer. It is worth noting that preliminary laboratory tests gave an excellent result.
In particular, scientists tried about ten configurations of peptides and settled on one family that had the greatest effect in this “temporary bomb” – with the average size of the platinum nanoparticle being less than 2.5 nanometers wide, which is also an achievement in a certain sense. After conducting several tests on various cancer cells, they found that such a compound successfully bypasses healthy cells – which was the aim of the study.